EVALUATION OF FIRST TRIMESTER CONTINGENT TEST FOR DOWN ’ S SYNDROME SCREENING
نویسندگان
چکیده
منابع مشابه
First- and second-trimester evaluation of risk for Down syndrome.
OBJECTIVE To investigate the differences in costs and outcomes of Down syndrome screening using data from the First and Second Trimester Evaluation of Risk (FASTER) Trial. METHODS Seven possible screening options for Down syndrome were compared: 1) Triple Screen-maternal serum alpha fetoprotein, estriol, and hCG; 2) Quad-maternal serum alpha fetoprotein, estriol, hCG, and Inhibin A; 3) Combin...
متن کاملAge independent first trimester screening for Down syndrome: improvement in test performance.
OBJECTIVE The aim of this study was to compare screening performance for Down syndrome of the absolute risk (AR) method to the first trimester combined test (FCT) at different maternal ages. METHODS There was a retrospective analysis of 32,448 FCT. AR was defined as final risk divided by maternal age risk. RESULTS The likelihood of receiving a true prediction was comparable between both met...
متن کاملNuchal translucency measurement in first trimester Down syndrome screening.
(1) Approximately three in every four fetuses with Down syndrome have increased nuchal translucency (NT), which is a larger than normal build-up of fluid at the back of the neck. (2) The ultrasound measurement of NT between 11 and 14 weeks' gestation, in combination with the mother's age and the levels of placental biochemical markers in her blood, can be used to detect approximately 84% of fet...
متن کاملFactors predicting a positive pregnancy screening test at first trimester
Background: For every pregnant woman, it is possible to have a child with chromosomal abnormalities. Although this possibility is not very high, by performing screening tests and considering the mother's background factors, we can largely realize the real extent of this possibility. Many comorbidities (like high blood pressure, diabetes, and obesity) and high-risk exposures (like alcohol consu...
متن کاملFirst-trimester screening for Down's syndrome.
The aim of the present study was to evaluate the efficacy of the first trimester screening for Down syndrome (DS) in an unselected low-risk Finnish population. The study involved 4,617 women who attended screening between the 8th and 14th weeks of pregnancy in 1998-2000. They gave a blood sample for the measurement of pregnancy associated plasma protein A (PAPP-A) and free beta human chorionic ...
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ژورنال
عنوان ژورنال: Journal of Evolution of Medical and Dental Sciences
سال: 2015
ISSN: 2278-4748,2278-4802
DOI: 10.14260/jemds/2015/1413